Comprised of faculty that span pharmaceutical and pharmacological research, 药物科学系正在扩大和加强其研究组合.
Existing areas of expertise include drug delivery, drug discovery, epigenetics, 生物分析技术, cell signaling, pharmacokinetics, pharmacodynamics, 和神经科学(查看以下最近的学术活动列表,以进一步了解该系成员正在进行的研究).
除了药学博士课程的教学课程外,该系还支持药学科学的学士和硕士学位课程.
Departmental faculty are centralized in the Biosciences Research Building (BRB).
学术活动报告
2020年学术活动报告
下面列出的活动是由全球十大赌博靠谱的平台药学系的成员,从1月1日开始, 2020 - December 31, 2020.
* ACPHS教员以粗体表示.
Awards
Christopher L. Cioffi 2020 奥尔巴尼药学与健康科学学院 Researcher of the Year Award.
Presentations & Conferences
Regional
K. Jin, 基质成分与乳腺癌之间通过分泌因子的相互作用促进肿瘤生长和转移, Nanobioseminar, 纳米科学学院 & 工程纽约州立大学理工学院. 2020年4月1日,纽约州奥尔巴尼.
K. Jin, 基质成分与内分泌抵抗性乳腺癌之间通过分泌因子的相互作用促进肿瘤生长和转移, ACPHS年度研究论坛, Albany NY, April 17, 2020.
M. Musteata and Galke D.:“使用新开发的聚丙烯腈SpinTip微萃取装置测量睾酮游离浓度”,在第68届asm会议上发表, Houston, TX, 2020年6月(更改为在线格式).
M. Musteata and Galke D.:“生物相容性聚丙烯腈微萃取装置的发展”,发表于第十届年度研究研讨会, ACPHS, Albany, NY, April 2020.
Abstracts
Sumit Kamat*, Sonia Parikh和 Manish B. Shah. Crystal Structure of CYP2C9*8 Genetic Variant Bound to an Anti-Hypertensive Drug Losartan. 实验生物学2020,圣地亚哥,加州. (*入选Datablitz Daily talk,并获得美国实验治疗药理学学会(ASPET)颁发的研究生旅行奖,参加会议. 因COVID-19会议取消.
迪伦·戴维*,索尼娅·帕里克和 Manish B. Shah. Insights into the Effect of Genetic Variation in CYP2C9 (*11) on Drug Binding. 实验生物学2020,圣地亚哥,加州. 因新冠肺炎疫情,会议取消. *Received undergraduate student travel stipend from the 奥尔巴尼药学与健康科学学院, and the 药物科学系 to attend the meeting. 因COVID-19会议取消
Invited
C. Cioffi, Photoswitchable ORG25543 congener enables optical control of glycine transporter. 第30届ACPHS年度研究研讨会, 奥尔巴尼药学与健康科学学院, Albany, New York, US, April 17, 2020.
M. Shah, 年度研究研讨会讲台会议-“人类细胞色素P450 2C9遗传多态性的功能和结构基础:对*2变异影响的见解”, April 17, ACPHS, Albany, NY.
Posters
K. Jin, Adipsin promotes tumor progression in ESR1 mutant breast cancer cells. AACR Virtual Annual Meeting II, June 22-24, 2020.
Nast N and K. Jin. HOXB7过表达细胞与基质细胞间串扰分泌因子的鉴定与验证. ACPHS年度研究论坛, Albany NY, April 16, 2020.
Pandithar S and K. Jin. 基质成分与内分泌抵抗性乳腺癌之间通过分泌因子的相互作用促进肿瘤生长和转移. ACPHS年度研究论坛, Albany NY, April 16, 2020.
Malone MK and K. Jin. Adipsin promotes tumor progression in ESR1 mutant ER+ breast cancer cells. ACPHS年度研究论坛, Albany NY, April 16, 2020.
Outside Services
编辑和期刊评审经验
Christopher L. Cioffi, "药物化学杂志", Reviewer, 2010-Present
Christopher L. Cioffi, "Journal of Organic Chemistry", Reviewer, 2010-Present
Christopher L. Cioffi, "Medicinal Chemistry Letters", Reviewer, 2010-Present
Christopher L. Cioffi, "Bioorganic and Medicinal Chemistry Letters", Reviewer, 2010-Present
Christopher L. Cioffi, "Current Pharmaceutical Design", Reviewer, 2010-Present
Christopher L. Cioffi, "Journal of Pharmacology and Experimental Therapeutics", Reviewer, 2019-Present
Christopher L. Cioffi, "Neuroscience and Behavioral Reviews", Reviewer, 2021
Christopher L. Cioffi, " 《全球十大赌博靠谱的平台》,审稿人,2021年
Christopher L. Cioffi, "Frontiers in Molecular Neuroscience"; working on the launch of a new section: “Pain Mechanisms and Modulators”, Associate Editor, 2021.
Christopher L. Cioffi, "Topics in Medicinal Chemistry"; serving as an editor and chapter contributor for a new volume in Topics in Medicinal Chemistry focused on Drug Delivery Challenges and Novel Therapeutic Approaches for Retinal Diseases. Volume Editor. 2018-2020.
Manish B. Shah, NIH MSFA Study Section (Macromolecular Structure and Function A) - 02/2020. 亲自参与.
Manish B. Shah, 应邀为化学信息与建模杂志(ACS)和药物代谢与处置杂志(ASPET)审阅一篇手稿.
检讨委员会及委员会
Christopher L. Cioffi 美国国立卫生研究院, review panel to evaluate U18 Research Demonstration – Cooperative Agreement applications; Step Up for Substance Use Disorders (SUD); NIH/NIDA Study Section ZDA1 SKM-D (6), June, 2020. Ad Hoc Member
Christopher L. Cioffi 美国国立卫生研究院, small business panel on Drug Discovery for Aging, Neuropsychiatric and Neurologic Disorders; NIH ZRG1 ETTN-H (11), November, 2020 – Present. Member.
Manish B. Shah, 当选ASPET委员-执行委员会成员(2020年7月至2023年6月)-药物代谢和处置部门.
Manish B. Shah, Nominated for Secretary/Treasurer for ASPET – Drug metabolism and disposition division.
Manish B. Shah, 受邀担任第40届中西部酶化学会议学生和博士后海报奖竞赛评委, October 2020 – Virtual from the University of Texas at Arlington.
Manish B. Shah, 学生暑期研究奖:BSPS本科生Thomas Yarbrough在实验室研究CYP2C9基因多态性.
M. MUSTEATA, 《全球十大赌博靠谱的平台》杂志副主编.
Publications
National
M. MUSTEATA, Cibotaru D., Celestin M.N., Kane M., and Musteata F.M.: “Simultaneous Determination of Free Concentration, Total Concentration, 和等离子体结合力,《全球十大赌博靠谱的平台》, 110(3), p. 1401 - 1411, http://doi.org/10.1016/j.xphs.2020.12.001, 2020.
M. MUSTEATA, LaPorte B. and Musteata F.M.: “Increasing the Accuracy of Total Body Clearance Measurement,《全球十大赌博靠谱的平台》, 109(6), p. 2079 - 2089, http://doi.org/10.1016/j.xphs.2020.03.002, 2020.
HAIAN ZHENG, Shargel and Yu’s Applied Biopharmaceutics and Pharmacokinetics, 8th Edition, 第十四章静脉输液, Murray P . Ducharme和Leon Shargel编辑, McGraw-Hill, 2020.
Books
C. L. Cioffi, (2020) Volume Editor: Drug Delivery Challenges and Novel Therapeutic Approaches for Retinal Diseases: chapter author; Introduction: Overview of the Human Eye, Mammalian Retina, 以及类视黄醇视觉周期. In:药物化学专题. Springer, Berlin, Heidelberg; ISBN 978-3-030-56618-0.
Peer Review
C. L. Cioffi, Muthuraman, P.; Raja, A.; Varadi, A.; Racz, B.; Petrukhin, K. 稳定转甲状腺素四聚体的视黄醇结合蛋白4双特异性拮抗剂的发现:脚手架跳跃, optimization, 临床前药理学评估作为两种常见的年龄相关合并症的潜在治疗方法. J. Med. Chem. 2020, 63, 11054-11084; PMID: 32878437.
Mostyn, S. N.; Sarker, S.; Muthuraman, P.; Raja, A.; Shimmon, S.; Rawling, T.; Cioffi, C. L.; Vandenberg, R. J. Photoswitchable ORG25543 congener enables optical control of glycine transporter 2. ACS Chem. Neurosci. 2020, 11, 1250-1258; PMID: 32191428.
Recommended in Faculty Opinions (F1000): Lowe J: Faculty Opinions Recommendation of [Cioffi CL et al., J. Med. Chem. 2020, 63, 11054-11084]. 在教师意见,2020年9月20日.
Malone MS, Smrekar K, Park S, Blakely B, Walter A, Nasta N, Park J, Considine M, Danilova L, Pandey N, Fertig E, Popel A, and Jin K*. TNBC微环境中基质细胞分泌的细胞因子作为癌症治疗的潜在靶点:实验和生物信息学预测. Cancer Biol Ther. 2020年6月2日;21(6):560-569.
K. Jin, 癌症研究的同行评审, Frontier Oncology, Drug Design, 发展与治疗, JECC, Cancer Medicine.
Sonia Parikh, Chiara Evans, Juliet Obi, Qinghai Zhang, Keiko Maekawa, Karen Glass, and Manish B. Shah*. 氯沙坦复合物中细胞色素P450 2C9*2的结构:遗传多态性的影响. 分子药理学. 2020. 98: 529-539. (Article figure selected for the Cover illustration of the November 2020 issue) (*Corresponding author)
Grants
Christopher L. Cioffi Title: 萎缩性老年性黄斑变性合并常见形式的老年性淀粉样蛋白疾病的药物治疗 Number: R01EY028549-01; NIH/NEI. Collaborators: 康斯坦丁·彼得鲁欣博士.D.,哥伦比亚大学,纽约,纽约州. Total Funds: $1,487,698. 资助期日期: 02/01/2018 – 01/31/2021 (no-cost extension: end date 01/31/2022). Role: 首席研究员(MPI).
Christopher L. Cioffi Title: Discovery and Development of Novel Glycine Transporter-2 Inhibitors for the Treatment of Neuropathic Pain. Number: 1R01DA048879-01; NIH/NIDA Collaborators:罗伯特·范登堡博士.D.他来自澳大利亚悉尼大学 . Total Funds: $1,832,790. Dates of Funding: 09/30/2019 – 06/30/2023. Role: 联络主要研究员.
Kideok Jin, Title: The role of secreted factors in crosstalk between endocrine resistant breast cancer and stroma. Grantor: 2020-2021年ACPHS发现奖学金. Total Funds: $5,000. Dates: 5/25/2021 – 6/30/2021. Role: 首席研究员.
Manish B. Shah, Title: Genetic and Structural Determinants of Warfarin and Losartan Binding to Cytochrome P450 2C9. Grantor: American Heart Association, Institutional Research Enhancement Award. 19AIREA34450040. Funding Amount: $154,000. Date: 07/01/2019 – 06/30/2021. Role: 首席研究员